Novel Transcriptomic Signatures in Blood and Brain Predictive of Behavioral Issues in PWS
Funded Year: 2020Dr. Godler’s lab is interested in identifying early predictors of autism and serious mental illness in PWS. In their preliminary data, they have found that inflammatory pathways linked to UBE3A (a key gene that regulates normal brain development and immune cell function) were affected differently in PWS caused by uniparental disomy (UPD),...