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Foundation for Prader-Willi Blog | Research (42)

What's for dinner? Mandometer anyone?

So, here's a different approach. A new study looks at the use of a computerized device in helping to modify eating behavior in typically developing obese adolescents.

Topics: Research

Long-Term Safety and Benefits of Growth Hormone Therapy for PWS

Several new reports on growth hormone (GH) therapy support the benefits of GH use in PWS, while continuing the trend of a reassuring safety profile.

Topics: Research

Seizure Disorder in Prader-Willi Syndrome

Although it's rarely mentioned in clinical descriptions of PWS, anyone who hangs around families with PWS knows that seizures seem to occur much more frequently in those with PWS than typical individuals. Even in cases where a seizure disorder is nev...

Topics: Research

Linking Learning with Neurodevelopmental Functioning - Final Report

This project was funded by the Foundation for Prader Willi Research in 2006 and conducted by Drs. Gregory Olley and Anne Wheeler and their team at the University of North Carolina, Chapel Hill (UNC), Center for Development and Learning. Dr. Wheeler i...

Topics: Research

Growth Hormone Therapy Does Not Worsen Scoliosis

The incidence of scoliosis in Prader-Willi syndrome is quite high (~30% in children under the age 10; up to ~80% in kids over the age of 10, compared to <3% in the general population). Because moderate to severe scoliosis can be associated with si...

Topics: Research

Adrenal Insufficiency and PWS

Several recent studies have begun to look more carefully at the causes of death in PWS, particularly in cases where death was sudden and/or unexpected. A review of 64 cases of death in children with PWS noted a high occurrence of respiratory infectio...

Topics: Research

Peptide YY and Obesity: A Promising New Examination

Obese individuals often have a deficiency in peptide YY (PYY), a hormone that is produced by endocrine "L" cells of the lower gastrointestinal tract, the stomach and the brainstem. Low levels of PYY may be a predisposing factor to the development of ...

Topics: Research

Brain-Derived Neurotrophic Factor; Its Role in Obesity

This is a reprint from The Gathered View, courtesy of PWSA (USA). Obesity and problems with overeating can be influenced by a number of factors in the brain. One such factor is brain-derived neurotrophic factor (BDNF), which is involved in eating and...

Topics: Research

An Obsessive Compulsive Mouse

Obsessive-Compulsive Disorder (OCD) affects about 2% of the population. It is characterized by persistent intrusive thoughts (obsessions), repetitive actions (compulsions), and excessive anxiety. As anyone who know someone with PWS can appreciate, OC...

Topics: Research